ProDigest

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Life Sciences Database

in het nederlands

FlandersBio offers an up-to-date life sciences database containing all the life sciences companies with biotech activity in Flanders, and all FlandersBio members. The guide provides easy and fast access to the local life sciences community.

Website: http://www.prodigest.be
Email:
Phone: +32 9 264 59 78
FlandersBio Member
More address details

Business Focus

ProDigest provides customized solutions to the operators in the market of food, functional food and pharmaceutical industry. They offer services in the field of gastrointestinal transit, bioavailability and metabolism of compounds based on the application of an extensive in vitro technology platform including a dynamic simulation model of the gastrointestinal tract. This technology platform is extended with expertise and access to animal trials and proof-of-concept human intervention studies.

Company Profile

ProDigest is a spin-off company from the Laboratory of Microbial Ecology and Technology (LabMET), located at Ghent University (Belgium) and was founded by dr. ir. Sam Possemiers, dr. Massimo Marzorati and dr. ir. Willy Verstraete.

ProDigest's services in the field of gastrointestinal transit, bioavailability and metabolism are based on the application of an extensive in vitro technology platform which was developed at LabMET and which is organized round a dynamic simulation model of the gastrointestinal tract, called the Simulator of the Human Intestinal Microbial Ecosystem (SHIME). This technology platform is combined with a wide range of in vitro assays, animal trials and proof-of-concept human intervention studies.

From in vitro to human studies, ProDigest offers a complete toolbox for gastrointestinal studies, to support your product development and functional food claim substantiation.

Science & Technology or Services

Main interest:

Evaluation of the efficacy of innovative food ingredients towards specific endpoints
Selection of the most effective food ingredient
Evaluation of specific formulations containing an active ingredient

ProDigest focus:

Product testing, selection and evaluation
Services from in vitro to human trials
- Small-scale in vitro screening experiments (metabolism, effect on the microbial community/bacterial attachment)
- Identification of active compounds or precursors and isolation of microorganisms for biotechnological applications
- Solubility studies and absorption modeling
- SHIME experiments: short and long term evaluation of the intestinal fate of specific compounds or formulations
- Host-microbe interaction studies using attachment models and cell cultures
- In vivo validation using animal models
- Proof-of-concept validation in human trials