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Life Sciences Database

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FlandersBio offers an up-to-date life sciences database containing all the life sciences companies with biotech activity in Flanders, and all FlandersBio members. The guide provides easy and fast access to the local life sciences community.

FlandersBio beschikt over een geüpdate databank met een overzicht van de Vlaamse bedrijven met biotechactiviteit en alle FlandersBio-leden. De databank verleent een makkelijke en vlugge toegang tot de lokale biowetenschappen-gemeenschap.

PharmaDiagnostics

Website: http://www.pharmadiagnostics.com
Email:
Phone: +32 2 481 60 35
FlandersBio Member
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Business Focus

PharmaDiagnostics is the first to enable label-free SPR screening on a standard plate-reader. Using derivatized gold nanoparticles in solution, SoPRanoTM enables sensitive, robust and reproducible screening in high-throughput. SoPRanoTM can be applied in small molecule and protein screening, including receptor-ligand binding, and antibody screening. Products & services include ADME and physico-chemical properties, and custom assay development in the above areas.

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Company Profile

PharmDiagnostics is a research platform technology company. Our SoPRanoTM platform is unique in enabling sensitive and high throughput label-free screening without the need for dedicated instrumentation. 

We develop and supply assay kits using specialised assay reagents and protocols to companies engaged in the discovery of both small molecule and protein therapeutics.

Current products include the SoPRano CA1 assay kit which enables users to build and run their own high throughput label-free assays, and a range of functional assay kits for ADME. We also offer custom assay development and screening services.

Science & Technology or Services

Surface Plasmon Resonance (SPR) is now an established label-free analytical technique. However, instrumentation costs and low throughput can limit broad adoption of the technique in early discovery research.

SoPRanoTM has taken this established principle and by using colloidal gold nano-particles makes it available on standard laboratory equipment. These particles can be derivatised with the protein target of interest, for example; upon ligand interaction a quantifiable change in optical density occurs which can be measured on a standard plate-reader.

This technique offers simple homogenous assay protocols, is sensitive, robust and reproducible, and has potential for very high throughput, limited only by throughput of your liquid handling equipment and plate-reader speed.

Product description

PharmaDiagnostics develops and supplies SoPRanoTM screening kits and services as follows:

  • CA1 kits enable users to build and run their own high-throughput label-free assays. Kits are available in a range of sizes and contain reagents and protocols for coupling proteins to SoPRanoTM gold nanoparticles and for their use in screening.
  • SoPRanoTM ADME assay kits for the following properties:
    • HSA and AGP ligand binding
    • pKa
    • Redox potential
    • Blood Brain Barrier
    • Bioavailability

We also offer assay development and screening services.

More info

Address: I&I Center Brussels
Z.1 Researchpark 310
1731 Zellik
Belgium

Route: Via Google Maps
Website: http://www.pharmadiagnostics.com

Phone: +32 2 481 60 35
Foundation date: 3/2007
Email: enquiries@pharmadiagnostics.co...

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PwC Belgium Xintera Consulting Pilipili productontwerp Oxyrane Belgium Cryo-Save Labs (Life Sciences) InvertTox MSD R.I.C. MINT Europe P95 Becton Dickinson Benelux Fugeia Thema Group Search & Selection Bird & Bird Landen Pharmachem Peira Alphastemsource L.E.D. Techno Andersen Products De Valck Consultants by Altran Strategus Enzo Life Sciences AlzProtect Hugin Mugin research DMSC. Dutch Medical & Science Consultancy Innofocus ChinArt Evolved Analytics Europe PNO Consultants Vesalius Biocapital Partners

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