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Life Sciences Database

Databank Biowetenschappen

in het nederlands in english

FlandersBio offers an up-to-date life sciences database containing all the life sciences companies with biotech activity in Flanders, and all FlandersBio members. The guide provides easy and fast access to the local life sciences community.

FlandersBio beschikt over een geüpdate databank met een overzicht van de Vlaamse bedrijven met biotechactiviteit en alle FlandersBio-leden. De databank verleent een makkelijke en vlugge toegang tot de lokale biowetenschappen-gemeenschap.

Genzyme

Website: http://www.genzyme.be
Email:
Phone: +32 14 56 49 11
FlandersBio Member
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Business Focus

Genzyme is a global biopharmaceutical company helping patients in more than 100 countries. Genzyme is Sanofi’s global center of excellence in rare diseases and multiple sclerosis (MS). In Geel, Belgium, Genzyme has a manufacturing facility to produce therapeutic protein products through cell culture. The main product is recombinant alpha-glucosidase, the enzyme replacement therapy for Pompe disease, a rare genetic, often fatal, disease of the muscle.

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Company Profile

Genzyme's commitment to innovation continues today with research into novel approaches to genetic disease, cancer, heart disease, and other areas of unmet medical need. Around 10,000 Genzyme employees in offices around the globe, of which about 3,400 in Europe, serve patients in over 100 countries.

Subsidiaries in Belgium:

  • Genzyme Belgium NV, founded in 1992, has offices in Zaventem, Brussels, holding Corporate Affairs Europe and Sales & Marketing Belgium-Luxemburg (employees 45).
  • Genzyme BVBA founded in 2001 located in Geel, a large manufacturing site for biopharmaceuticals (employees >450).

Science & Technology or Services

Genzyme has strong development programs using multiple technologies to investigate cancer, cardiovascular diseases, and immune diseases. In research and development, the company takes a pragmatic approach that gives freedom to apply diverse technologies to specific medical areas. These technologies include proteins, polymers, small molecules, biomaterials, cell therapy and gene therapy.

Product description

Personalized Genetic Health and Cardiovascular:

  • Enzyme replacement treatment for Type 1 Gaucher disease.
  • Enzyme replacement treatment for Fabry disease.
  • Enzyme replacement treatment for Mucopolysaccharidosis I (MPS I).
  • Enzyme replacement treatment for Pompe disease.
  • A cholesterol binding polymer

Renal:

  • A unique calcium-free, metal-free phosphate binder indicated for the control of serum phosphorus in patients with Chronic Kidney Disease on hemodialysis.
  • A vitamin D2 analogue indicated for the treatment of secondary hyperparathyroidism in patients with Chronic Kidney Disease Stages.

Biosurgery:

  • A local therapy that provides lubrication for the knee joint and helps to reduce or to stop pain in an osteoarthritic knee.
  • Autologous cultured chondrocytes to help repair damaged knee cartilage in patients with injuries caused by acute or repetitive trauma.

Hematology and Oncology:

  • A humanized monoclonal antibody indicated for the treatment of B-cell chronic lymphocytic leukemia (B-CLL) in patients.
  • A small molecule was granted marketing approval for the treatment of children with refractory or relapsed acute lymphoblastic leukemia (ALL). ALL is the most common form of pediatric leukemia
  • Recombinant human hormone as an adjunctive diagnostic used in follow-up screenings of cancer patients with well-differentiated thyroid cancer who have had their thyroid glands removed.
  • A small molecule used to mobilize stem cells from the bone marrow to the peripheral blood to facilitate harvesting by apheresis
  • A chemotherapy drug used in the treatment of hematological malignancies
  • An immunosuppressive polyclonal antibody that is used in conjunction with concomitant immunosuppression to treat acute rejection in transplant patients.

Alliances

Genzyme seeks strategic collaborations to expand its portfolio of commercialized products and services, to supplement its product pipeline, and to access complementary research, technology, and development capabilities. The company focuses on first-rate science and on opportunities that address well-defined patient populations with unmet or underserved medical need.

Some major partnerships:

  • Biomarin - enzyme replacement therapy for Mucopolysaccharidosis type I
  • Isis Pharmaceutical: Developing Mipomersen for high risk cardiovascular disease
  • PTC: Developing Ataluren for Duchenne muscular dystrophy and cystic fibrosis

More info

Address: Cipalstraat 8
2440 Geel
Belgium

Route: Via Google Maps
Website: http://www.genzyme.be

Phone: +32 14 56 49 11
Fax: +32 14 56 49 80
Foundation date: 2001
Email: luc.kupers@genzyme.com

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